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β-glucuronidase use as a single internal control gene may confound analysis in FMR1 mRNA toxicity studies

Relationships between Fragile X Mental Retardation 1 (FMR1) mRNA levels in blood and intragenic FMR1 CGG triplet expansions support the pathogenic role of RNA gain of function toxicity in premutation (PM: 55–199 CGGs) related disorders. Real-time PCR (RT-PCR) studies reporting these findings normali...

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Detalles Bibliográficos
Autores principales:	Kraan, Claudine M., Cornish, Kim M., Bui, Quang M., Li, Xin, Slater, Howard R., Godler, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825026/ https://www.ncbi.nlm.nih.gov/pubmed/29474364 http://dx.doi.org/10.1371/journal.pone.0192151

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