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Detection of mitochondrial DNA with 4977 bp deletion in leukocytes of patients with ischemic stroke

BACKGROUND: Coronary artery disease is associated with a common mitochondrial DNA alteration, a 4977 bp deletion (mtDNA(4977)). The role of mtDNA(4977) in ischemic stroke is unknown. METHODS: Real-time quantitative PCR was performed to quantify total mtDNA and mtDNA(4977) in leukocytes in 283 ischem...

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Detalles Bibliográficos
Autores principales:	Huang, Yu-hua, Chen, Chiung-Mei, Lee, Yun-Shien, Chang, Kuo-Hsuan, Chen, Huei-Wen, Chen, Yi-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825052/ https://www.ncbi.nlm.nih.gov/pubmed/29474453 http://dx.doi.org/10.1371/journal.pone.0193175

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