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SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs

Stem cells are defined by their capacities to self-renew and generate progeny of multiple lineages. The transcription factor SOX2 has key roles in the regulation of stem cell characteristics, but whether SOX2 achieves these functions through similar mechanisms in distinct stem cell populations is no...

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Detalles Bibliográficos
Autores principales: Hagey, Daniel W., Klum, Susanne, Kurtsdotter, Idha, Zaouter, Cecile, Topcic, Danijal, Andersson, Olov, Bergsland, Maria, Muhr, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825159/
https://www.ncbi.nlm.nih.gov/pubmed/29432416
http://dx.doi.org/10.1371/journal.pgen.1007224