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Endogenous overexpression of an active phosphorylated form of DNA polymerase β under oxidative stress in Trypanosoma cruzi

Trypanosoma cruzi is exposed during its life to exogenous and endogenous oxidative stress, leading to damage of several macromolecules such as DNA. There are many DNA repair pathways in the nucleus and mitochondria (kinetoplast), where specific protein complexes detect and eliminate damage to DNA. O...

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Detalles Bibliográficos
Autores principales: Rojas, Diego A., Urbina, Fabiola, Moreira-Ramos, Sandra, Castillo, Christian, Kemmerling, Ulrike, Lapier, Michel, Maya, Juan Diego, Solari, Aldo, Maldonado, Edio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825160/
https://www.ncbi.nlm.nih.gov/pubmed/29432450
http://dx.doi.org/10.1371/journal.pntd.0006220

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