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Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains
The majority of the proteins encoded in the genomes of eukaryotes contain more than one domain. Reasons for high prevalence of multi-domain proteins in various organisms have been attributed to higher stability and functional and folding advantages over single-domain proteins. Despite these advantag...
Autores principales: | Vishwanath, Sneha, de Brevern, Alexandre G., Srinivasan, Narayanaswamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825166/ https://www.ncbi.nlm.nih.gov/pubmed/29432415 http://dx.doi.org/10.1371/journal.pcbi.1006008 |
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