Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

Infection and tissue damage induces assembly of supramolecular organizing centres (SMOCs)), such as the Toll-like receptor (TLR) MyDDosome, to co-ordinate inflammatory signaling. SMOC assembly is thought to drive digital all-or-none responses, yet TLR activation by diverse microbes induces anything...

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Detalles Bibliográficos
Autores principales: Latty, Sarah Louise, Sakai, Jiro, Hopkins, Lee, Verstak, Brett, Paramo, Teresa, Berglund, Nils A, Cammarota, Eugenia, Cicuta, Pietro, Gay, Nicholas J, Bond, Peter J, Klenerman, David, Bryant, Clare E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825206/
https://www.ncbi.nlm.nih.gov/pubmed/29368691
http://dx.doi.org/10.7554/eLife.31377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825206/
https://www.ncbi.nlm.nih.gov/pubmed/29368691
http://dx.doi.org/10.7554/eLife.31377

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