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Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting

Cellular decision‐making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactive states, resulting in bursts of RNA synthesis. Furthermore,...

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Detalles Bibliográficos
Autores principales: Fritzsch, Christoph, Baumgärtner, Stephan, Kuban, Monika, Steinshorn, Daria, Reid, George, Legewie, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825209/
https://www.ncbi.nlm.nih.gov/pubmed/29476006
http://dx.doi.org/10.15252/msb.20177678