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Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting
Cellular decision‐making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactive states, resulting in bursts of RNA synthesis. Furthermore,...
Autores principales: | Fritzsch, Christoph, Baumgärtner, Stephan, Kuban, Monika, Steinshorn, Daria, Reid, George, Legewie, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825209/ https://www.ncbi.nlm.nih.gov/pubmed/29476006 http://dx.doi.org/10.15252/msb.20177678 |
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