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Mms19 is a mitotic gene that permits Cdk7 to be fully active as a Cdk-activating kinase

Mms19 encodes a cytosolic iron-sulphur assembly component. We found that Drosophila Mms19 is also essential for mitotic divisions and for the proliferation of diploid cells. Reduced Mms19 activity causes severe mitotic defects in spindle dynamics and chromosome segregation, and loss of zygotic Mms19...

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Detalles Bibliográficos
Autores principales: Nag, Rishita Narendra, Niggli, Selina, Sousa-Guimarães, Sofia, Vazquez-Pianzola, Paula, Suter, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825849/
https://www.ncbi.nlm.nih.gov/pubmed/29361561
http://dx.doi.org/10.1242/dev.156802