Sulfur-Containing Monoterpenoids as Potential Antithrombotic Drugs: Research in the Molecular Mechanism of Coagulation Activity Using Pinanyl Sulfoxide as an Example

In this article we present the synthesis of enantiomerically pure sulfoxide and study the influence of this compound on hemostasis. Detailed NMR studies and molecular dynamics simulations using sodium dodecyl sulfate (SDS) membrane models indicated that the bicyclic fragment of sulfoxide was embedde...

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Detalles Bibliográficos
Autores principales: Nikitina, Liliya E., Kiselev, Sergei V., Startseva, Valeriya A., Bodrov, Andrei V., Azizova, Zulfiya R., Shipina, Olga T., Fedyunina, Inna V., Boichuk, Sergei V., Lodochnikova, Olga A., Klochkov, Vladimir V., Galiullina, Leisan F., Khaliullina, Aliya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825891/
https://www.ncbi.nlm.nih.gov/pubmed/29515444
http://dx.doi.org/10.3389/fphar.2018.00116

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