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Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
Parkinson's disease (PD) is characterized by intracellular inclusions of aggregated and misfolded α-Synuclein (α-Syn), and the loss of dopaminergic (DA) neurons in the brain. The resulting motor abnormalities mark the progression of PD, while non-motor symptoms can already be identified during...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825910/ https://www.ncbi.nlm.nih.gov/pubmed/29515354 http://dx.doi.org/10.3389/fnins.2018.00080 |