Pharmacokinetics, Safety, and Tolerability of Cefiderocol, a Novel Siderophore Cephalosporin for Gram-Negative Bacteria, in Healthy Subjects

Cefiderocol is a novel parenteral siderophore cephalosporin that shows potent efficacy against various Gram-negative bacteria, including carbapenem-resistant strains, in vitro and in preclinical models of infection. The aim of the present study was to evaluate the pharmacokinetics (PK), safety, and...

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Detalles Bibliográficos
Autores principales: Saisho, Yutaka, Katsube, Takayuki, White, Scott, Fukase, Hiroyuki, Shimada, Jingoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826143/
https://www.ncbi.nlm.nih.gov/pubmed/29311072
http://dx.doi.org/10.1128/AAC.02163-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826143/
https://www.ncbi.nlm.nih.gov/pubmed/29311072
http://dx.doi.org/10.1128/AAC.02163-17

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