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NSG2 (ORF19.273) Encoding Protein Controls Sensitivity of Candida albicans to Azoles through Regulating the Synthesis of C14-Methylated Sterols

Antifungal azole drugs inhibit the synthesis of ergosterol and cause the accumulation of sterols containing a 14α-methyl group, which is related to the properties of cell membrane. Due to the frequent recurrence of fungal infections and clinical long-term prophylaxis, azole resistance is increasing...

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Detalles Bibliográficos
Autores principales:	Lv, Quan-Zhen, Qin, Yu-Lin, Yan, Lan, Wang, Liang, Zhang, Chuyue, Jiang, Yuan-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826172/ https://www.ncbi.nlm.nih.gov/pubmed/29515531 http://dx.doi.org/10.3389/fmicb.2018.00218

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