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Autoradiography of (3)H-pirenzepine and (3)H-AFDX-384 in Mouse Brain Regions: Possible Insights into M(1), M(2), and M(4) Muscarinic Receptors Distribution
Autoradiography helps to determine the distribution and density of muscarinic receptor (MR) binding sites in the brain. However, it relies on the selectivity of radioligands toward their target. (3)H-Pirenzepine is commonly believed to label predominantly M(1)MR, (3)H-AFDX-384 is considered as M(2)M...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826229/ https://www.ncbi.nlm.nih.gov/pubmed/29515448 http://dx.doi.org/10.3389/fphar.2018.00124 |