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Characterization of luteinizing hormone-releasing hormone receptor type I (LH-RH-I) as a potential molecular target in OCM-1 and OCM-3 human uveal melanoma cell lines

INTRODUCTION: Uveal melanoma (UM) is the most common primary intraocular malignancy with very poor prognosis. Conventional chemotherapy only rarely prolongs the survival, therefore patients require novel treatment modalities. The discovery of specific receptors for hypothalamic hormones on cancer ce...

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Detalles Bibliográficos
Autores principales: Sipos, Eva, Dobos, Nikoletta, Rozsa, David, Fodor, Klara, Olah, Gabor, Szabo, Zsuzsanna, Szekvolgyi, Lorant, Schally, Andrew V, Halmos, Gabor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826244/
https://www.ncbi.nlm.nih.gov/pubmed/29503568
http://dx.doi.org/10.2147/OTT.S148174