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Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide
Toll-like receptor 4 (TLR4) induces inflammation in response to both pathogen- and host-derived molecules. Lipopolysaccharide (LPS) recognition by TLR4 has been shown to occur across the amniotes, but endogenous signaling through TLR4 has not been validated outside of placental mammals. To determine...
Autores principales: | Loes, Andrea N., Bridgham, Jamie T., Harms, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826337/ https://www.ncbi.nlm.nih.gov/pubmed/29515592 http://dx.doi.org/10.3389/fimmu.2018.00304 |
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