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Junctional E-cadherin/p120-catenin Is Correlated with the Absence of Supporting Cells to Hair Cells Conversion in Postnatal Mice Cochleae

Notch inhibition is known to generate supernumerary hair cells (HCs) at the expense of supporting cells (SCs) in the mammalian inner ear. However, inhibition of Notch activity becomes progressively less effective at inducing SC-to-HC conversion in the postnatal cochlea and balance organs as the anim...

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Detalles Bibliográficos
Autores principales: Luo, Wen-wei, Wang, Xin-wei, Ma, Rui, Chi, Fang-lu, Chen, Ping, Cong, Ning, Gu, Yu-yan, Ren, Dong-dong, Yang, Juan-mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826362/
https://www.ncbi.nlm.nih.gov/pubmed/29515364
http://dx.doi.org/10.3389/fnmol.2018.00020