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Chymase Inhibitor as a Novel Therapeutic Agent for Non-alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) is characterized by inflammation and fibrosis, in addition to steatosis, of the liver, but no therapeutic agents have yet been established. The mast cell protease chymase can generate angiotensin II, matrix metalloproteinase-9 and transforming growth factor-β, al...

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Detalles Bibliográficos
Autores principales: Takai, Shinji, Jin, Denan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826365/
https://www.ncbi.nlm.nih.gov/pubmed/29515450
http://dx.doi.org/10.3389/fphar.2018.00144

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