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The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis

BACKGROUND: Recently, immune-checkpoint blockade has shown striking clinical results in different cancer patients. However, a significant inter-individual and inter-tumor variability exists among different cancers. The expression of the toxins granzyme A (GZMA) and perforin 1 (PRF1), secreted by eff...

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Detalles Bibliográficos
Autores principales:	Roufas, Constantinos, Chasiotis, Dimitrios, Makris, Anestis, Efstathiades, Christodoulos, Dimopoulos, Christos, Zaravinos, Apostolos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826382/ https://www.ncbi.nlm.nih.gov/pubmed/29515971 http://dx.doi.org/10.3389/fonc.2018.00027

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