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Analysis of age-related changes in psychosine metabolism in the human brain

α-Synuclein aggregation has been linked to Gaucher’s disease (GD) and Krabbe’s disease (KD), lysosomal conditions affecting glycosphingolipid metabolism. α-Synuclein pathology has been directly attributed to the dysregulation of glycosphingolipids in both conditions, specifically to increased galact...

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Detalles Bibliográficos
Autores principales: Marshall, Michael S., Jakubauskas, Benas, Bogue, Wil, Stoskute, Monika, Hauck, Zane, Rue, Emily, Nichols, Matthew, DiAntonio, Lisa L., van Breemen, Richard B., Kordower, Jeffrey H., Saavedra-Matiz, Carlos A., Bongarzone, Ernesto R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537/
https://www.ncbi.nlm.nih.gov/pubmed/29481565
http://dx.doi.org/10.1371/journal.pone.0193438