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Analysis of age-related changes in psychosine metabolism in the human brain
α-Synuclein aggregation has been linked to Gaucher’s disease (GD) and Krabbe’s disease (KD), lysosomal conditions affecting glycosphingolipid metabolism. α-Synuclein pathology has been directly attributed to the dysregulation of glycosphingolipids in both conditions, specifically to increased galact...
Autores principales: | Marshall, Michael S., Jakubauskas, Benas, Bogue, Wil, Stoskute, Monika, Hauck, Zane, Rue, Emily, Nichols, Matthew, DiAntonio, Lisa L., van Breemen, Richard B., Kordower, Jeffrey H., Saavedra-Matiz, Carlos A., Bongarzone, Ernesto R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537/ https://www.ncbi.nlm.nih.gov/pubmed/29481565 http://dx.doi.org/10.1371/journal.pone.0193438 |
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