Identification of PMN-released mutagenic factors in a co-culture model for colitis-associated cancer

Microsatellite instability (MSI) is present in ulcerative colitis (UC) and colitis-associated colorectal cancers (CAC). Certain factors released by polymorphonuclear cells (PMNs) may drive mucosal frameshift mutations resulting in MSI and cancer. Here, we applied a co-culture system with PMNs and co...

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Detalles Bibliográficos
Autores principales: Granofszky, Nicolas, Lang, Michaela, Khare, Vineeta, Schmid, Gerald, Scharl, Theresa, Ferk, Franziska, Jimenez, Kristine, Knasmüller, Siegfried, Campregher, Christoph, Gasche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826597/
https://www.ncbi.nlm.nih.gov/pubmed/29106440
http://dx.doi.org/10.1093/carcin/bgx118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826597/
https://www.ncbi.nlm.nih.gov/pubmed/29106440
http://dx.doi.org/10.1093/carcin/bgx118

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