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Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β
The various symptomatic outcomes of cutaneous leishmaniasis relates to the type and potency of its underlying inflammatory responses. Presence of the cytoplasmic Leishmania RNA virus-1 (LRV1) within Leishmania guyanensis, worsens lesional inflammation and parasite burden, as the viral dsRNA genome a...
Autores principales: | Hartley, Mary-Anne, Eren, Remzi O., Rossi, Matteo, Prevel, Florence, Castiglioni, Patrik, Isorce, Nathalie, Desponds, Chantal, Lye, Lon-Fye, Beverley, Stephen M., Drexler, Stefan K., Fasel, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826701/ https://www.ncbi.nlm.nih.gov/pubmed/29487860 http://dx.doi.org/10.15698/mic2018.03.619 |
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