Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation

Despite continuous improvements in treatment of glioblastoma, tumor recurrence and therapy resistance still occur in a high proportion of patients. One underlying reason for this radioresistance might be the presence of glioblastoma cancer stem cells (GSCs), which feature high DNA repair capability....

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Detalles Bibliográficos
Autores principales: Lesueur, Paul, Chevalier, François, El-Habr, Elias A., Junier, Marie-Pierre, Chneiweiss, Hervé, Castera, Laurent, Müller, Etienne, Stefan, Dinu, Saintigny, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826933/
https://www.ncbi.nlm.nih.gov/pubmed/29483558
http://dx.doi.org/10.1038/s41598-018-22022-4

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