Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

Neuronal loss in Parkinson’s disease (PD) is associated with aberrant mitochondrial function and impaired proteostasis. Identifying the mechanisms that link these pathologies is critical to furthering our understanding of PD pathogenesis. Using human pluripotent stem cells (hPSCs) that allow compari...

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Detalles Bibliográficos
Autores principales: Ryan, Tammy, Bamm, Vladimir V., Stykel, Morgan G., Coackley, Carla L., Humphries, Kayla M., Jamieson-Williams, Rhiannon, Ambasudhan, Rajesh, Mosser, Dick D., Lipton, Stuart A., Harauz, George, Ryan, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827019/
https://www.ncbi.nlm.nih.gov/pubmed/29483518
http://dx.doi.org/10.1038/s41467-018-03241-9

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