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Chemotherapeutic Drug Based Metal–Organic Particles for Microvesicle‐Mediated Deep Penetration and Programmable pH/NIR/Hypoxia Activated Cancer Photochemotherapy

A novel metal–organic particle (MOP) based nanodrug formed by mild self‐assembly of chemotherapeutic drugs, including banoxantrone and doxorubicin, through Cu(II)‐mediated coordination effects, is reported. In this nanodrug, Cu(II) acts as a bridge to join AQ4N and DOX, and then, self‐assembly of [‐...

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Detalles Bibliográficos
Autores principales: Zhang, Da, Wu, Ming, Cai, Zhixiong, Liao, Naishun, Ke, Kun, Liu, Hongzhi, Li, Ming, Liu, Gang, Yang, Huanghao, Liu, Xiaolong, Liu, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827097/
https://www.ncbi.nlm.nih.gov/pubmed/29619314
http://dx.doi.org/10.1002/advs.201700648