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Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses
Low oxygen environments and accumulation of hypoxia-inducible factors (HIFs) are features of infected and inflamed tissues. Here, we summarize our current knowledge on oxygen levels found in Leishmania-infected tissues and discuss which mechanisms potentially contribute to local tissue oxygenation i...
Autores principales: | Schatz, Valentin, Neubert, Patrick, Rieger, Franz, Jantsch, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827161/ https://www.ncbi.nlm.nih.gov/pubmed/29520262 http://dx.doi.org/10.3389/fimmu.2018.00216 |
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