The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)

Although S-1 chemotherapy is used widely as postoperative adjuvant chemotherapy for gastric cancer, some patients experience diarrhea during treatment. The patient was a 39-year-old woman who underwent distal gastrectomy for gastric cancer and who had started S-1 chemotherapy as postoperative adjuva...

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Autores principales: Ota, Kazuhiro, Takeuchi, Toshihisa, Kodama, Kouki, Ozaki, Haruhiko, Harada, Satoshi, Kojima, Yuichi, Nouda, Sadaharu, Goto, Masahiro, Higuchi, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827313/
https://www.ncbi.nlm.nih.gov/pubmed/29093427
http://dx.doi.org/10.2169/internalmedicine.9519-17
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author Ota, Kazuhiro
Takeuchi, Toshihisa
Kodama, Kouki
Ozaki, Haruhiko
Harada, Satoshi
Kojima, Yuichi
Nouda, Sadaharu
Goto, Masahiro
Higuchi, Kazuhide
author_facet Ota, Kazuhiro
Takeuchi, Toshihisa
Kodama, Kouki
Ozaki, Haruhiko
Harada, Satoshi
Kojima, Yuichi
Nouda, Sadaharu
Goto, Masahiro
Higuchi, Kazuhide
author_sort Ota, Kazuhiro
collection PubMed
description Although S-1 chemotherapy is used widely as postoperative adjuvant chemotherapy for gastric cancer, some patients experience diarrhea during treatment. The patient was a 39-year-old woman who underwent distal gastrectomy for gastric cancer and who had started S-1 chemotherapy as postoperative adjuvant chemotherapy 1 week before her presentation. She experienced severe diarrhea immediately after starting the course of S-1 tablets. Capsule endoscopy revealed severe S-1-induced enteritis with extensive mucosal injury in the ileum and red intestinal fluid due to the oozing of blood in the ileum. After reducing the dosage of S-1, her diarrhea became milder, and she was able to continue S-1 chemotherapy.
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spelling pubmed-58273132018-02-28 The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video) Ota, Kazuhiro Takeuchi, Toshihisa Kodama, Kouki Ozaki, Haruhiko Harada, Satoshi Kojima, Yuichi Nouda, Sadaharu Goto, Masahiro Higuchi, Kazuhide Intern Med Case Report Although S-1 chemotherapy is used widely as postoperative adjuvant chemotherapy for gastric cancer, some patients experience diarrhea during treatment. The patient was a 39-year-old woman who underwent distal gastrectomy for gastric cancer and who had started S-1 chemotherapy as postoperative adjuvant chemotherapy 1 week before her presentation. She experienced severe diarrhea immediately after starting the course of S-1 tablets. Capsule endoscopy revealed severe S-1-induced enteritis with extensive mucosal injury in the ileum and red intestinal fluid due to the oozing of blood in the ileum. After reducing the dosage of S-1, her diarrhea became milder, and she was able to continue S-1 chemotherapy. The Japanese Society of Internal Medicine 2017-11-01 2018-02-01 /pmc/articles/PMC5827313/ /pubmed/29093427 http://dx.doi.org/10.2169/internalmedicine.9519-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ota, Kazuhiro
Takeuchi, Toshihisa
Kodama, Kouki
Ozaki, Haruhiko
Harada, Satoshi
Kojima, Yuichi
Nouda, Sadaharu
Goto, Masahiro
Higuchi, Kazuhide
The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title_full The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title_fullStr The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title_full_unstemmed The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title_short The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)
title_sort capsule endoscopy findings in s-1-induced enteritis with severe diarrhea during adjuvant chemotherapy for gastric cancer (with video)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827313/
https://www.ncbi.nlm.nih.gov/pubmed/29093427
http://dx.doi.org/10.2169/internalmedicine.9519-17
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