Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome

Mycobacterium colombiense (M. colombiense) is a member of the Mycobacterium avium complex (MAC). To our knowledge, this is the third case report of an M. colombiense infection. An 80-year-old man, immunocompromised by myelodysplastic syndrome (MDS), developed a skin rash with exfoliation and eruptio...

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Autores principales: Inagaki, Yuichiro, Ito, Tatsuya, Kato, Tomonori, Ono, Yoshitaka, Sawa, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827328/
https://www.ncbi.nlm.nih.gov/pubmed/29093379
http://dx.doi.org/10.2169/internalmedicine.7890-16
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author Inagaki, Yuichiro
Ito, Tatsuya
Kato, Tomonori
Ono, Yoshitaka
Sawa, Masashi
author_facet Inagaki, Yuichiro
Ito, Tatsuya
Kato, Tomonori
Ono, Yoshitaka
Sawa, Masashi
author_sort Inagaki, Yuichiro
collection PubMed
description Mycobacterium colombiense (M. colombiense) is a member of the Mycobacterium avium complex (MAC). To our knowledge, this is the third case report of an M. colombiense infection. An 80-year-old man, immunocompromised by myelodysplastic syndrome (MDS), developed a skin rash with exfoliation and eruption on his face and scalp. Mycobacteria were detected in pus samples. Broad-range polymerase chain reaction (PCR) revealed the mycobacteria to be M. colombiense. The lesions resolved after daily administration of rifampicin, ethambutol, and clarithromycin. In conclusion, broad-range PCR identified this rare mycobacterium, allowing for the administration of appropriate combination antibiotic therapy.
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spelling pubmed-58273282018-02-28 Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome Inagaki, Yuichiro Ito, Tatsuya Kato, Tomonori Ono, Yoshitaka Sawa, Masashi Intern Med Case Report Mycobacterium colombiense (M. colombiense) is a member of the Mycobacterium avium complex (MAC). To our knowledge, this is the third case report of an M. colombiense infection. An 80-year-old man, immunocompromised by myelodysplastic syndrome (MDS), developed a skin rash with exfoliation and eruption on his face and scalp. Mycobacteria were detected in pus samples. Broad-range polymerase chain reaction (PCR) revealed the mycobacteria to be M. colombiense. The lesions resolved after daily administration of rifampicin, ethambutol, and clarithromycin. In conclusion, broad-range PCR identified this rare mycobacterium, allowing for the administration of appropriate combination antibiotic therapy. The Japanese Society of Internal Medicine 2017-11-01 2018-02-01 /pmc/articles/PMC5827328/ /pubmed/29093379 http://dx.doi.org/10.2169/internalmedicine.7890-16 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Inagaki, Yuichiro
Ito, Tatsuya
Kato, Tomonori
Ono, Yoshitaka
Sawa, Masashi
Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title_full Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title_fullStr Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title_full_unstemmed Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title_short Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome
title_sort disseminated cutaneous infection of mycobacterium colombiense in a patient with myelodysplastic syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827328/
https://www.ncbi.nlm.nih.gov/pubmed/29093379
http://dx.doi.org/10.2169/internalmedicine.7890-16
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