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Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells

Oncolytic viruses gain cancer specificity in several ways. Like the majority of viruses, they grow better in cancer cells that are defective in mounting the host response to viruses. Often, they are attenuated by deletion or mutation of virulence genes that counteract the host response or are natura...

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Detalles Bibliográficos
Autores principales:	Petrovic, Biljana, Leoni, Valerio, Gatta, Valentina, Zaghini, Anna, Vannini, Andrea, Campadelli-Fiume, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Gene Delivery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827396/ https://www.ncbi.nlm.nih.gov/pubmed/29263257 http://dx.doi.org/10.1128/JVI.02122-17

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