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MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2

Chemokines are the principal regulators of leukocyte migration and are essential for initiation and maintenance of inflammation. Atypical chemokine receptor 2 (ACKR2) binds and scavenges proinflammatory CC-chemokines, regulates cutaneous T-cell positioning, and limits the spread of inflammation in v...

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Detalles Bibliográficos
Autores principales: Shams, Kave, Kurowska-Stolarska, Mariola, Schütte, Fabian, Burden, A. David, McKimmie, Clive S., Graham, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827444/
https://www.ncbi.nlm.nih.gov/pubmed/29279330
http://dx.doi.org/10.1074/jbc.M117.809780