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Fast tracking in adult living donor liver transplantation: A case series of 15 patients

BACKGROUND AND AIMS: Fast tracking (FT) for more efficacious use of resources may be difficult after living donor liver transplantation (LDLT) due to a partial liver graft, complex vascular anastomoses and longer operating time. Our study was aimed at reporting our experience with FT (on table extub...

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Autores principales: Bhangui, Pooja, Bhangui, Prashant, Gupta, Nikunj, Jolly, Annu Sarin, Bhalotra, Seema, Sharma, Nishant, Soin, AS, Vohra, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827479/
https://www.ncbi.nlm.nih.gov/pubmed/29491518
http://dx.doi.org/10.4103/ija.IJA_566_17
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author Bhangui, Pooja
Bhangui, Prashant
Gupta, Nikunj
Jolly, Annu Sarin
Bhalotra, Seema
Sharma, Nishant
Soin, AS
Vohra, Vijay
author_facet Bhangui, Pooja
Bhangui, Prashant
Gupta, Nikunj
Jolly, Annu Sarin
Bhalotra, Seema
Sharma, Nishant
Soin, AS
Vohra, Vijay
author_sort Bhangui, Pooja
collection PubMed
description BACKGROUND AND AIMS: Fast tracking (FT) for more efficacious use of resources may be difficult after living donor liver transplantation (LDLT) due to a partial liver graft, complex vascular anastomoses and longer operating time. Our study was aimed at reporting our experience with FT (on table extubation) in LDLT recipients. A secondary objective of our study was to look at defining a subgroup of patients who could be prospectively planned for FT. METHODS: We studied the demographics and outcomes of 15 LDLT recipients extubated immediately in the operating suite based on an uneventful intraoperative course, haemodynamic stability after graft reperfusion and improvement of metabolic parameters post-implantation and vascular anastomoses. RESULTS: Twelve recipients were males, and mean age, body mass index (BMI) and Model for End Stage Liver Disease (MELD) score were 43 ± 12 years, 23 ± 3 kg/m(2) and 15.5 ± 6, respectively, most were Child–Turcotte–Pugh Class B. Diabetes and hypothyroidism were present in 1 and 2 patients, respectively. Post-extubation, none required immediate re-intubation and one patient needed non-invasive ventilation for 2 h. CONCLUSION: Fast tracked recipients were young, with a low BMI, low MELD scores, minimal comorbidities and good immediate graft function post-reperfusion.
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spelling pubmed-58274792018-02-28 Fast tracking in adult living donor liver transplantation: A case series of 15 patients Bhangui, Pooja Bhangui, Prashant Gupta, Nikunj Jolly, Annu Sarin Bhalotra, Seema Sharma, Nishant Soin, AS Vohra, Vijay Indian J Anaesth Original Article BACKGROUND AND AIMS: Fast tracking (FT) for more efficacious use of resources may be difficult after living donor liver transplantation (LDLT) due to a partial liver graft, complex vascular anastomoses and longer operating time. Our study was aimed at reporting our experience with FT (on table extubation) in LDLT recipients. A secondary objective of our study was to look at defining a subgroup of patients who could be prospectively planned for FT. METHODS: We studied the demographics and outcomes of 15 LDLT recipients extubated immediately in the operating suite based on an uneventful intraoperative course, haemodynamic stability after graft reperfusion and improvement of metabolic parameters post-implantation and vascular anastomoses. RESULTS: Twelve recipients were males, and mean age, body mass index (BMI) and Model for End Stage Liver Disease (MELD) score were 43 ± 12 years, 23 ± 3 kg/m(2) and 15.5 ± 6, respectively, most were Child–Turcotte–Pugh Class B. Diabetes and hypothyroidism were present in 1 and 2 patients, respectively. Post-extubation, none required immediate re-intubation and one patient needed non-invasive ventilation for 2 h. CONCLUSION: Fast tracked recipients were young, with a low BMI, low MELD scores, minimal comorbidities and good immediate graft function post-reperfusion. Medknow Publications & Media Pvt Ltd 2018-02 /pmc/articles/PMC5827479/ /pubmed/29491518 http://dx.doi.org/10.4103/ija.IJA_566_17 Text en Copyright: © 2018 Indian Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Bhangui, Pooja
Bhangui, Prashant
Gupta, Nikunj
Jolly, Annu Sarin
Bhalotra, Seema
Sharma, Nishant
Soin, AS
Vohra, Vijay
Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title_full Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title_fullStr Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title_full_unstemmed Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title_short Fast tracking in adult living donor liver transplantation: A case series of 15 patients
title_sort fast tracking in adult living donor liver transplantation: a case series of 15 patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827479/
https://www.ncbi.nlm.nih.gov/pubmed/29491518
http://dx.doi.org/10.4103/ija.IJA_566_17
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