Cargando…

Clonally diverse CD38(+)HLA-DR(+)CD8(+) T cells persist during fatal H7N9 disease

Severe influenza A virus (IAV) infection is associated with immune dysfunction. Here, we show circulating CD8(+) T-cell profiles from patients hospitalized with avian H7N9, seasonal IAV, and influenza vaccinees. Patient survival reflects an early, transient prevalence of highly activated CD38(+)HLA-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhongfang, Zhu, Lingyan, Nguyen, Thi H. O., Wan, Yanmin, Sant, Sneha, Quiñones-Parra, Sergio M., Crawford, Jeremy Chase, Eltahla, Auda A., Rizzetto, Simone, Bull, Rowena A., Qiu, Chenli, Koutsakos, Marios, Clemens, E. Bridie, Loh, Liyen, Chen, Tianyue, Liu, Lu, Cao, Pengxing, Ren, Yanqin, Kedzierski, Lukasz, Kotsimbos, Tom, McCaw, James M., La Gruta, Nicole L., Turner, Stephen J., Cheng, Allen C., Luciani, Fabio, Zhang, Xiaoyan, Doherty, Peter C., Thomas, Paul G., Xu, Jianqing, Kedzierska, Katherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827521/ https://www.ncbi.nlm.nih.gov/pubmed/29483513 http://dx.doi.org/10.1038/s41467-018-03243-7

Ejemplares similares

Avian Influenza Viruses, Inflammation, and CD8(+) T Cell Immunity
por: Wang, Zhongfang, et al.
Publicado: (2016)

High expression of CD38 and MHC class II on CD8(+) T cells during severe influenza disease reflects bystander activation and trogocytosis
por: Jia, Xiaoxiao, et al.
Publicado: (2021)

On the Role of CD8(+) T Cells in Determining Recovery Time from Influenza Virus Infection
por: Cao, Pengxing, et al.
Publicado: (2016)

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8(+) T cells
por: Wang, Zhongfang, et al.
Publicado: (2015)

Impact of sequencing depth and read length on single cell RNA sequencing data of T cells
por: Rizzetto, Simone, et al.
Publicado: (2017)

Viral burden, inflammatory milieu and CD8(+) T‐cell responses to influenza virus in a second‐generation thiazolide (RM‐5061) and oseltamivir combination therapy study
por: Nüssing, Simone, et al.
Publicado: (2020)

Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
por: Eltahla, Auda A., et al.
Publicado: (2015)

The Mechanisms for Within-Host Influenza Virus Control Affect Model-Based Assessment and Prediction of Antiviral Treatment
por: Cao, Pengxing, et al.
Publicado: (2017)

Single-Cell Approach to Influenza-Specific CD8(+) T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection
por: Sant, Sneha, et al.
Publicado: (2018)

Modelling the Effect of MUC1 on Influenza Virus Infection Kinetics and Macrophage Dynamics
por: Li, Ke, et al.
Publicado: (2021)

Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses
por: Li, Ke, et al.
Publicado: (2023)

Broad CD8(+) T cell cross-recognition of distinct influenza A strains in humans
por: Grant, Emma J., et al.
Publicado: (2018)

Immune Signature of Enhanced Functional Avidity CD8(+) T Cells in vivo Induced by Vaccinia Vectored Vaccine
por: Hu, Zhidong, et al.
Publicado: (2017)

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+) T cells
por: Sant, Sneha, et al.
Publicado: (2020)

CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
por: Hensen, Luca, et al.
Publicado: (2021)

Understanding the Determinants of BnAb Induction in Acute HCV Infection
por: Underwood, Alexander P., et al.
Publicado: (2018)

Identification of human progenitors of exhausted CD8(+) T cells associated with elevated IFN-γ response in early phase of viral infection
por: Cai, Curtis, et al.
Publicado: (2022)

Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment
por: Eltahla, Auda A., et al.
Publicado: (2017)

SATB1 ensures appropriate transcriptional programs within naïve CD8(+) T cells
por: Nüssing, Simone, et al.
Publicado: (2022)

Envelope-Specific IgG3 and IgG1 Responses Are Associated with Clearance of Acute Hepatitis C Virus Infection
por: Walker, Melanie R., et al.
Publicado: (2020)

CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells
por: Zhang, Linxia, et al.
Publicado: (2020)

Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation
por: Sant, Sneha, et al.
Publicado: (2019)

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
por: Nguyen, Thi H. O., et al.
Publicado: (2021)

Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies
por: Walker, Melanie R., et al.
Publicado: (2019)

Maintenance of the EBV-specific CD8(+) TCRαβ repertoire in immunosuppressed lung transplant recipients
por: Nguyen, Thi HO, et al.
Publicado: (2017)

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude
por: Quinn, Kylie M., et al.
Publicado: (2017)

Metabolic characteristics of CD8(+) T cell subsets in young and aged individuals are not predictive of functionality
por: Quinn, Kylie M., et al.
Publicado: (2020)

The ABC of Major Histocompatibility Complexes and T Cell Receptors in Health and Disease
por: Kedzierska, Katherine, et al.
Publicado: (2020)

Universal immunity to influenza must outwit immune evasion
por: Quiñones-Parra, Sergio, et al.
Publicado: (2014)

Induction of Protective CD4(+) T Cell-Mediated Immunity by a Leishmania Peptide Delivered in Recombinant Influenza Viruses
por: Kedzierska, Katherine, et al.
Publicado: (2012)

Improving the ex vivo expansion of human tumor-reactive CD8 + T cells by targeting toll-like receptors
por: Qiu, Chenli, et al.
Publicado: (2022)

Publisher Correction: Metabolic characteristics of CD8(+) T cell subsets in young and aged individuals are not predictive of functionality
por: Quinn, Kylie M., et al.
Publicado: (2020)

Development of Skewed Functionality of HIV-1-Specific Cytotoxic CD8(+) T Cells from Primary to Early Chronic Phase of HIV Infection
por: Wang, Wanhai, et al.
Publicado: (2012)

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8(+) T cells
por: Thiele, Daniel, et al.
Publicado: (2020)

Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection
por: Cao, Pengxing, et al.
Publicado: (2019)

Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control
por: Bolton, Kirsty J., et al.
Publicado: (2015)

SARS-CoV-2-specific CD4(+) T cells are associated with long-term persistence of neutralizing antibodies
por: Wang, Zhongfang, et al.
Publicado: (2022)

A method for near full-length amplification and sequencing for six hepatitis C virus genotypes
por: Bull, Rowena A., et al.
Publicado: (2016)

Class I histone deacetylase inhibition promotes CD8 T cell activation in ovarian cancer
por: McCaw, Tyler R., et al.
Publicado: (2020)

Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
por: van de Sandt, Carolien E., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6rcav3shvfuugevnnuf1uij0g6