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Targeted Mutation of NGN3 Gene Disrupts Pancreatic Endocrine Cell Development in Pigs

The domestic pig is an attractive model for biomedical research because of similarities in anatomy and physiology to humans. However, key gaps remain in our understanding of the role of developmental genes in pig, limiting its full potential. In this publication, the role of NEUROGENIN 3 (NGN3), a t...

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Detalles Bibliográficos
Autores principales: Sheets, Timothy P., Park, Ki-Eun, Park, Chi-Hun, Swift, Steven M., Powell, Anne, Donovan, David M., Telugu, Bhanu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827570/
https://www.ncbi.nlm.nih.gov/pubmed/29483633
http://dx.doi.org/10.1038/s41598-018-22050-0