Cargando…

Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and its potential mechanisms

The aims of the present study were to examine signaling mechanisms underlying transforming growth factor β1 (TGF-β1)-induced airway smooth muscle cells (ASMCs) proliferation and to determine the effect of adenosine monophosphate-activated protein kinase (AMPK) activation on TGF-β1-induced ASMCs prol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Yilin, Liu, Lu, Li, Shaojun, Wang, Ke, Ke, Rui, Shi, Wenhua, Wang, Jian, Yan, Xin, Zhang, Qianqian, Wang, Qingting, Chai, Limin, Xie, Xinming, Li, Manxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827654/ https://www.ncbi.nlm.nih.gov/pubmed/29483552 http://dx.doi.org/10.1038/s41598-018-21812-0

Ejemplares similares

Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells
por: Li, Shaojun, et al.
Publicado: (2017)

SphK1/S1P mediates TGF-β1-induced proliferation of pulmonary artery smooth muscle cells and its potential mechanisms
por: Wang, Jian, et al.
Publicado: (2018)

S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation
por: Wang, Jian, et al.
Publicado: (2021)

Ubiquitin-specific protease 7 mediates platelet-derived growth factor-induced pulmonary arterial smooth muscle cells proliferation
por: Zhu, Yanting, et al.
Publicado: (2021)

5-HT induces PPAR γ reduction and proliferation of pulmonary artery smooth muscle cells via modulating GSK-3β/β-catenin pathway
por: Ke, Rui, et al.
Publicado: (2017)

Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway
por: Ke, Rui, et al.
Publicado: (2016)

Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells
por: Xie, Xinming, et al.
Publicado: (2018)

Activation of PPAR-γ prevents TERT-mediated pulmonary vascular remodeling in MCT-induced pulmonary hypertension
por: Hussain, Tafseel, et al.
Publicado: (2023)

Increased DCLK1 correlates with the malignant status and poor outcome in malignant tumors: a meta-analysis
por: Shi, Wenhua, et al.
Publicado: (2017)

ERK/Drp1‐dependent mitochondrial fission contributes to HMGB1‐induced autophagy in pulmonary arterial hypertension
por: Feng, Wei, et al.
Publicado: (2021)

Association of interleukin-17a rs2275913 gene polymorphism and asthma risk: a meta-analysis
por: Zhai, Cui, et al.
Publicado: (2018)

Overexpression of DJ-1 correlates with aggressive clinicopathological characteristics and poor prognosis in malignant tumors: a meta-analysis
por: Wang, Qingting, et al.
Publicado: (2018)

The value of long noncoding RNA CASC2 as a biomarker of prognosis in carcinomas: a meta-analysis
por: Yan, Xin, et al.
Publicado: (2018)

Activation of AMPK Prevents Monocrotaline-Induced Extracellular Matrix Remodeling of Pulmonary Artery
por: Li, Shaojun, et al.
Publicado: (2016)

Clinicopathological and prognostic significance of leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) in malignant tumors: A meta-analysis
por: Zhang, Qianqian, et al.
Publicado: (2018)

The association between cystatin C and COPD: a meta-analysis and systematic review
por: Chai, Limin, et al.
Publicado: (2020)

Epidemiological features and temporal trends of HIV-negative tuberculosis burden from 1990 to 2019: a retrospective analysis based on the Global Burden of Disease Study 2019
por: Chen, Yuqian, et al.
Publicado: (2023)

Prediction of target genes for miR‐140‐5p in pulmonary arterial hypertension using bioinformatics methods
por: Li, Fangwei, et al.
Publicado: (2017)

MiR-182/Sestrin2 affects the function of asthmatic airway smooth muscle cells by the AMPK/mTOR pathway
por: Xiao, Yali, et al.
Publicado: (2021)

MiR-182/Sestrin2 affects the function of asthmatic airway smooth muscle cells by the AMPK/mTOR pathway
por: Xiao, Yali, et al.
Publicado: (2021)

Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation
por: Liu, Jin, et al.
Publicado: (2023)

TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases
por: Chen, Gang, et al.
Publicado: (2006)

Epigenetic Links to Airway Smooth Muscle Proliferation
por: Jia, Man, et al.
Publicado: (2019)

Quantitative CT parameters correlate with lung function in chronic obstructive pulmonary disease: A systematic review and meta-analysis
por: Wang, Yan, et al.
Publicado: (2023)

Clinicopathologic Features and Prognostic Implications of Golgi Phosphoprotein 3 in Non-small Cell Lung Cancer: A Meta-analysis
por: Shi, Wenhua, et al.
Publicado: (2019)

HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo
por: Zhang, Qianqian, et al.
Publicado: (2023)

The effect of Shenmai injection on the proliferation of Rat airway smooth muscle cells in asthma and underlying mechanism
por: Zhao, Limin, et al.
Publicado: (2013)

CFTR dysfunction in smooth muscle drives TGFβ dependent airway hyperreactivity
por: Kramer, Elizabeth L., et al.
Publicado: (2023)

A HuR/TGF-β1 feedback circuit regulates airway remodeling in airway smooth muscle cells
por: Wang, Na, et al.
Publicado: (2016)

Association Between Red Blood Cell Distribution Width–Albumin Ratio and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Study
por: Qiu, Yuanjie, et al.
Publicado: (2022)

Airway smooth muscle proliferation and survival is not modulated by mast cells
por: Kaur, D, et al.
Publicado: (2010)

Nomograms for Predicting Coexisting Cardiovascular Disease and Prognosis in Chronic Obstructive Pulmonary Disease: A Study Based on NHANES Data
por: Qiu, Yuanjie, et al.
Publicado: (2022)

Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Pulmonary Infectious Pathogens From Bronchoalveolar Lavage Samples
por: Chen, Yuqian, et al.
Publicado: (2021)

Inflammation signals airway smooth muscle cell proliferation in asthma pathogenesis
por: Khan, Mohammad Afzal
Publicado: (2013)

Cytokines and Growth Factors Promote Airway Smooth Muscle Cell Proliferation
por: Stamatiou, R., et al.
Publicado: (2012)

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma
por: Hernandez-Lara, Miguel Angel, et al.
Publicado: (2022)

Airway Smooth Muscle and Asthma
por: An, Steven, et al.
Publicado: (2023)

Effects of bronchial thermoplasty and cryoablation on airway smooth muscle
por: Li, Xuan, et al.
Publicado: (2021)

Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle
por: Wang, Lu, et al.
Publicado: (2019)

TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation
por: Wu, Lian-pan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_124hid5rrtvti9sqr8nslvemf7