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Normalization of cell associated antiretroviral drug concentrations with a novel RPP30 droplet digital PCR assay

Quantification of antiretroviral (ARV) drug concentrations in peripheral blood mononuclear cells (PBMCs) and tissue isolated mononuclear cells (TIMCs) from lymph node (LNMC) and rectum (RMC) is an important measure of bio-distribution. Normalization of drug concentrations is critical to represent ti...

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Detalles Bibliográficos
Autores principales: Dyavar, Shetty Ravi, Ye, Zhen, Byrareddy, Siddappa N., Scarsi, Kimberly K., Winchester, Lee C., Weinhold, Jonathan A., Fletcher, Courtney V., Podany, Anthony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827666/
https://www.ncbi.nlm.nih.gov/pubmed/29483619
http://dx.doi.org/10.1038/s41598-018-21882-0