Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy

Dominant mutations in GARS, encoding the ubiquitous enzyme glycyl-tRNA synthetase (GlyRS), cause peripheral nerve degeneration and Charcot-Marie-Tooth disease type 2D (CMT2D). This genetic disorder exemplifies a recurring paradigm in neurodegeneration, in which mutations in essential genes cause sel...

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Detalles Bibliográficos
Autores principales: Grice, Stuart J., Sleigh, James N., Zameel Cader, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827687/
https://www.ncbi.nlm.nih.gov/pubmed/29520219
http://dx.doi.org/10.3389/fnmol.2018.00055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827687/
https://www.ncbi.nlm.nih.gov/pubmed/29520219
http://dx.doi.org/10.3389/fnmol.2018.00055

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