Cargando…
ImmPort, toward repurposing of open access immunological assay data for translational and clinical research
Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypothe...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827693/ https://www.ncbi.nlm.nih.gov/pubmed/29485622 http://dx.doi.org/10.1038/sdata.2018.15 |
_version_ | 1783302517008891904 |
---|---|
author | Bhattacharya, Sanchita Dunn, Patrick Thomas, Cristel G. Smith, Barry Schaefer, Henry Chen, Jieming Hu, Zicheng Zalocusky, Kelly A. Shankar, Ravi D. Shen-Orr, Shai S. Thomson, Elizabeth Wiser, Jeffrey Butte, Atul J. |
author_facet | Bhattacharya, Sanchita Dunn, Patrick Thomas, Cristel G. Smith, Barry Schaefer, Henry Chen, Jieming Hu, Zicheng Zalocusky, Kelly A. Shankar, Ravi D. Shen-Orr, Shai S. Thomson, Elizabeth Wiser, Jeffrey Butte, Atul J. |
author_sort | Bhattacharya, Sanchita |
collection | PubMed |
description | Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components–Private Data, Shared Data, Data Analysis, and Resources—for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the Shared Data portal (www.immport.org/immport-open), which allows research data to be repurposed to accelerate the translation of new insights into discoveries. |
format | Online Article Text |
id | pubmed-5827693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-58276932018-03-19 ImmPort, toward repurposing of open access immunological assay data for translational and clinical research Bhattacharya, Sanchita Dunn, Patrick Thomas, Cristel G. Smith, Barry Schaefer, Henry Chen, Jieming Hu, Zicheng Zalocusky, Kelly A. Shankar, Ravi D. Shen-Orr, Shai S. Thomson, Elizabeth Wiser, Jeffrey Butte, Atul J. Sci Data Article Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components–Private Data, Shared Data, Data Analysis, and Resources—for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the Shared Data portal (www.immport.org/immport-open), which allows research data to be repurposed to accelerate the translation of new insights into discoveries. Nature Publishing Group 2018-02-27 /pmc/articles/PMC5827693/ /pubmed/29485622 http://dx.doi.org/10.1038/sdata.2018.15 Text en Copyright © 2018, The Author(s) http://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article. |
spellingShingle | Article Bhattacharya, Sanchita Dunn, Patrick Thomas, Cristel G. Smith, Barry Schaefer, Henry Chen, Jieming Hu, Zicheng Zalocusky, Kelly A. Shankar, Ravi D. Shen-Orr, Shai S. Thomson, Elizabeth Wiser, Jeffrey Butte, Atul J. ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title_full | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title_fullStr | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title_full_unstemmed | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title_short | ImmPort, toward repurposing of open access immunological assay data for translational and clinical research |
title_sort | immport, toward repurposing of open access immunological assay data for translational and clinical research |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827693/ https://www.ncbi.nlm.nih.gov/pubmed/29485622 http://dx.doi.org/10.1038/sdata.2018.15 |
work_keys_str_mv | AT bhattacharyasanchita immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT dunnpatrick immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT thomascristelg immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT smithbarry immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT schaeferhenry immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT chenjieming immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT huzicheng immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT zalocuskykellya immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT shankarravid immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT shenorrshais immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT thomsonelizabeth immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT wiserjeffrey immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch AT butteatulj immporttowardrepurposingofopenaccessimmunologicalassaydatafortranslationalandclinicalresearch |