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Bumetanide for autism: more eye contact, less amygdala activation
We recently showed that constraining eye contact leads to exaggerated increase of amygdala activation in autism. Here, in a proof of concept pilot study, we demonstrate that administration of bumetanide (a NKCC1 chloride importer antagonist that restores GABAergic inhibition) normalizes the level of...
Autores principales: | Hadjikhani, Nouchine, Åsberg Johnels, Jakob, Lassalle, Amandine, Zürcher, Nicole R., Hippolyte, Loyse, Gillberg, Christopher, Lemonnier, Eric, Ben-Ari, Yehezkel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827728/ https://www.ncbi.nlm.nih.gov/pubmed/29483603 http://dx.doi.org/10.1038/s41598-018-21958-x |
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