Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior

The RASopathy neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant genetic disorders. In NF1 patients, neurological issues may result from damaged myelin, and mice with a neurofibromin gene (Nf1) mutation show white matter (WM) defects including myelin decompaction. Using mous...

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Detalles Bibliográficos
Autores principales: López-Juárez, Alejandro, Titus, Haley E., Silbak, Sadiq H., Pressler, Joshua W., Rizvi, Tilat A., Bogard, Madeleine, Bennett, Michael R., Ciraolo, Georgianne, Williams, Michael T., Vorhees, Charles V., Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828008/
https://www.ncbi.nlm.nih.gov/pubmed/28423318
http://dx.doi.org/10.1016/j.celrep.2017.03.073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828008/
https://www.ncbi.nlm.nih.gov/pubmed/28423318
http://dx.doi.org/10.1016/j.celrep.2017.03.073

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