MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2

BACKGROUND: Interleukin-1β (IL-1β) is a pivotal proinflammatory cytokine that is strongly associated with the inflammation of gout. However, the underlying mechanism through which the production of IL-1β is regulated has not been fully elucidated. Our previous work identified that miR-302b had an im...

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Detalles Bibliográficos
Autores principales: Ma, Teng, Liu, Xiao, Cen, Zhifu, Xin, Chuan, Guo, Mingfeng, Zou, Chaoyu, Song, Wenpeng, Xie, Rou, Wang, Kailun, Zhou, Hong, Zhang, Jun, Wang, Zhen, Bian, Ce, Cui, Kaijun, Li, Jiong, Wei, Yu-Quan, Li, Jing, Zhou, Xikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828083/
https://www.ncbi.nlm.nih.gov/pubmed/29482609
http://dx.doi.org/10.1186/s13075-018-1528-9

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