A Case of Levamisole-Induced Agranulocytosis

A sixty-eight-year-old male with a past medical history of recurrent cocaine use presented to the emergency department with recurrent diarrhea and was found to have a white blood cell (WBC) count of 1.9 × 10(9)/L with agranulocytosis (absolute neutrophil count (ANC) of 95 cell/mm(3)). At admission,...

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Detalles Bibliográficos
Autores principales: Kassim, Thamer, Chintalacheruvu, Lakshmi, Bhatty, Osman, Selim, Mohammad, Diab, Osama, Nayfeh, Ali, Manikkam Umakanthan, Jayadev, Gbadamosi-Akindele, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828115/
https://www.ncbi.nlm.nih.gov/pubmed/29607229
http://dx.doi.org/10.1155/2018/7341835
Descripción
Sumario:A sixty-eight-year-old male with a past medical history of recurrent cocaine use presented to the emergency department with recurrent diarrhea and was found to have a white blood cell (WBC) count of 1.9 × 10(9)/L with agranulocytosis (absolute neutrophil count (ANC) of 95 cell/mm(3)). At admission, the patient disclosed that he used cocaine earlier during the day, and a urine drug screen tested positive for this. On hospital day one, the patient was found to have a fever with a maximum temperature of 313.6 K. After ruling out other causes and noting the quick turnaround of his neutropenia after four days of cocaine abstinence, the patient's neutropenia was attributed to levamisole-adulterated cocaine.

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