Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis

Specific therapies targeting cellular and molecular events of sepsis induced Acute Lung Injury (ALI) pathogenesis are lacking. We have reported a pivotal role for Nuclear Factors of Activated T cells (NFATc3) in regulating macrophage phenotype during sepsis induced ALI and subsequent studies demonst...

Descripción completa

Detalles Bibliográficos
Autores principales: Karpurapu, Manjula, Lee, Yong Gyu, Qian, Ziqing, Wen, Jin, Ballinger, Megan N., Rusu, Luiza, Chung, Sangwoon, Deng, Jing, Qian, Feng, Reader, Brenda F., Nirujogi, Teja Srinivas, Park, Gye Young, Pei, Dehua, Christman, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828182/
https://www.ncbi.nlm.nih.gov/pubmed/29535830
http://dx.doi.org/10.18632/oncotarget.24320

Ejemplares similares

Ejemplares similares