Cargando…

Overexpression of p54(nrb)/NONO induces differential EPHA6 splicing and contributes to castration-resistant prostate cancer growth

The non-POU domain-containing octamer binding protein p54(nrb)/NONO is a multifunctional nuclear protein involved in RNA splicing, processing, and transcriptional regulation of nuclear hormone receptors. Through chromosome copy number analysis via whole-exome sequencing, we revealed amplification of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamamoto, Ryuji, Osawa, Tsuyoshi, Sasaki, Yusuke, Yamamoto, Shogo, Anai, Motonobu, Izumi, Kouji, Matsumura, Yoshihiro, Sakai, Juro, Aburatani, Hiroyuki, Mizokami, Atsushi, Kodama, Tatsuhiko, Tanaka, Toshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828187/ https://www.ncbi.nlm.nih.gov/pubmed/29535823 http://dx.doi.org/10.18632/oncotarget.24063

Ejemplares similares

Nuclear scaffold protein p54(nrb)/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma
por: Shen, Mengqin, et al.
Publicado: (2021)

p54nrb/NonO and PSF promote U snRNA nuclear export by accelerating its export complex assembly
por: Izumi, Hiroto, et al.
Publicado: (2014)

Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content
por: Sasaki, Yusuke, et al.
Publicado: (2020)

RNA-binding protein p54(nrb)/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer
por: Shen, Mengqin, et al.
Publicado: (2022)

Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate
por: Sasaki, Yusuke, et al.
Publicado: (2019)

Regulation of PCGEM1 by p54/nrb in prostate cancer
por: Ho, Tsui-Ting, et al.
Publicado: (2016)

Selective PPARα Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis
por: Murakami, Kentaro, et al.
Publicado: (2022)

Immunodetection of nmt55/p54(nrb) isoforms in human breast cancer
por: Pavao, Matthew, et al.
Publicado: (2001)

Promoter-Dependent Translation Controlled by p54(nrb) and hnRNPM during Myoblast Differentiation
por: Ainaoui, Nadera, et al.
Publicado: (2015)

2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF
por: Shen, Wen, et al.
Publicado: (2015)

Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1
por: Vickers, Timothy A, et al.
Publicado: (2019)

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance
por: Li, Shuyi, et al.
Publicado: (2009)

Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background
por: Muramatsu, Masashi, et al.
Publicado: (2021)

Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation
por: Kondo, Ayano, et al.
Publicado: (2017)

PPARα activation directly upregulates thrombomodulin in the diabetic retina
por: Shiono, Akira, et al.
Publicado: (2020)

Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation
por: Shen, Wen, et al.
Publicado: (2017)

The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions
por: Eichler, Madeleine, et al.
Publicado: (2022)

An Unusual Prostate-Specific Antigen Decrease in an Advanced Castration-Resistant Prostate Cancer Patient with Intracerebral Hemorrhage Subsequently Treated with Luteinizing Hormone-Releasing Hormone Antagonist
por: Izumi, Kouji, et al.
Publicado: (2013)

Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in Ras-Induced Senescence
por: Kaneda, Atsushi, et al.
Publicado: (2011)

NONO and tumorigenesis: More than splicing
por: Feng, Peifu, et al.
Publicado: (2020)

Optimal treatment for castration-resistant prostate cancer
por: Izumi, Kouji, et al.
Publicado: (2014)

Understanding prostate-specific antigen dynamics in monitoring metastatic castration-resistant prostate cancer: implications for clinical practice
por: Mizokami, Atsushi, et al.
Publicado: (2017)

The suitability of NONO-TFE3 dual-fusion FISH assay as a diagnostic tool for NONO-TFE3 renal cell carcinoma
por: Liu, Ning, et al.
Publicado: (2020)

Enzalutamide versus abiraterone as a first-line endocrine therapy for castration-resistant prostate cancer (ENABLE study for PCa): a study protocol for a multicenter randomized phase III trial
por: Izumi, Kouji, et al.
Publicado: (2017)

Long response duration to pembrolizumab in metastatic, castration-resistant prostate cancer with microsatellite instability-high and neuroendocrine differentiation: A case report
por: Yoshida, Tsukasa, et al.
Publicado: (2022)

Transcriptional silencing of fetal hemoglobin expression by NonO
por: Li, Xinyu, et al.
Publicado: (2021)

PPARβ/δ activation of CD300a controls intestinal immunity
por: Tanaka, Toshiya, et al.
Publicado: (2014)

Suppressive Role of Androgen/Androgen Receptor Signaling via Chemokines on Prostate Cancer Cells
por: Izumi, Kouji, et al.
Publicado: (2019)

EPHA2, EPHA4, and EPHA7 Expression in Triple-Negative Breast Cancer
por: Nikas, Ilias, et al.
Publicado: (2022)

Persistent diarrhoea in a 5-month-old baby carrying Vibrio cholerae nonO1/nonO139 producing Haitian cholera toxin
por: Kumar, P., et al.
Publicado: (2017)

JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis
por: Abe, Yohei, et al.
Publicado: (2015)

EPHA2, EPHA4, and EPHA6 Expression in Uveal Melanomas: Searching for the Culprits of Neoplasia
por: Pergaris, Alexandros, et al.
Publicado: (2022)

Spatiotemporal dynamics of SETD5-containing NCoR–HDAC3 complex determines enhancer activation for adipogenesis
por: Matsumura, Yoshihiro, et al.
Publicado: (2021)

Enzalutamide Versus Abiraterone plus Prednisolone Before Chemotherapy for Castration-resistant Prostate Cancer: A Multicenter Randomized Controlled Trial
por: Izumi, Kouji, et al.
Publicado: (2022)

SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
por: Petti, Eleonora, et al.
Publicado: (2019)

PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer
por: Yin, Xin-Ke, et al.
Publicado: (2021)

Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism
por: Laurenzi, Tommaso, et al.
Publicado: (2022)

Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML
por: Zhang, Feifei, et al.
Publicado: (2022)

A novel NONO variant that causes developmental delay and cardiac phenotypes
por: Itai, Toshiyuki, et al.
Publicado: (2023)

Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch
por: Abe, Yohei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dais4msiptss47v0me237rumud