The hypoxia-responsive lncRNA NDRG-OT1 promotes NDRG1 degradation via ubiquitin-mediated proteolysis in breast cancer cells

Hypoxia can lead to solid tumor aggressiveness by driving multiple signaling pathways. Long non-coding RNAs respond to several extrinsic stimuli, causing changes in cancer cells by participating in multiple steps of gene expression. However, genomic profiling of long non-coding RNAs regulated by oxy...

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Detalles Bibliográficos
Autores principales: Lin, Hsin-Chen, Yeh, Ching-Ching, Chao, Lo-Yun, Tsai, Mong-Hsun, Chen, Hung-Hsin, Chuang, Eric Y., Lai, Liang-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828211/
https://www.ncbi.nlm.nih.gov/pubmed/29535820
http://dx.doi.org/10.18632/oncotarget.23732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828211/
https://www.ncbi.nlm.nih.gov/pubmed/29535820
http://dx.doi.org/10.18632/oncotarget.23732

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