Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks

BACKGROUND: Genome-wide association studies of Alzheimer’s disease (AD) have identified a number of significant risk loci, the majority of which lie in non-coding regions of the genome. The lack of causal alleles and considerable polygenicity remains a significant barrier to translation into mechani...

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Detalles Bibliográficos
Autores principales: Tansey, Katherine E., Cameron, Darren, Hill, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828245/
https://www.ncbi.nlm.nih.gov/pubmed/29482603
http://dx.doi.org/10.1186/s13073-018-0523-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828245/
https://www.ncbi.nlm.nih.gov/pubmed/29482603
http://dx.doi.org/10.1186/s13073-018-0523-8

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