Site-Directed Spin Labeling EPR for Studying Membrane Proteins

Site-directed spin labeling (SDSL) in combination with electron paramagnetic resonance (EPR) spectroscopy is a rapidly expanding powerful biophysical technique to study the structural and dynamic properties of membrane proteins in a native environment. Membrane proteins are responsible for performin...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahu, Indra D., Lorigan, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828257/
https://www.ncbi.nlm.nih.gov/pubmed/29607317
http://dx.doi.org/10.1155/2018/3248289
_version_ 1783302602719494144
author Sahu, Indra D.
Lorigan, Gary A.
author_facet Sahu, Indra D.
Lorigan, Gary A.
author_sort Sahu, Indra D.
collection PubMed
description Site-directed spin labeling (SDSL) in combination with electron paramagnetic resonance (EPR) spectroscopy is a rapidly expanding powerful biophysical technique to study the structural and dynamic properties of membrane proteins in a native environment. Membrane proteins are responsible for performing important functions in a wide variety of complicated biological systems that are responsible for the survival of living organisms. In this review, a brief introduction of the most popular SDSL EPR techniques and illustrations of recent applications for studying pertinent structural and dynamic properties on membrane proteins will be discussed.
format Online
Article
Text
id pubmed-5828257
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-58282572018-04-01 Site-Directed Spin Labeling EPR for Studying Membrane Proteins Sahu, Indra D. Lorigan, Gary A. Biomed Res Int Review Article Site-directed spin labeling (SDSL) in combination with electron paramagnetic resonance (EPR) spectroscopy is a rapidly expanding powerful biophysical technique to study the structural and dynamic properties of membrane proteins in a native environment. Membrane proteins are responsible for performing important functions in a wide variety of complicated biological systems that are responsible for the survival of living organisms. In this review, a brief introduction of the most popular SDSL EPR techniques and illustrations of recent applications for studying pertinent structural and dynamic properties on membrane proteins will be discussed. Hindawi 2018-01-23 /pmc/articles/PMC5828257/ /pubmed/29607317 http://dx.doi.org/10.1155/2018/3248289 Text en Copyright © 2018 Indra D. Sahu and Gary A. Lorigan. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sahu, Indra D.
Lorigan, Gary A.
Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title_full Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title_fullStr Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title_full_unstemmed Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title_short Site-Directed Spin Labeling EPR for Studying Membrane Proteins
title_sort site-directed spin labeling epr for studying membrane proteins
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828257/
https://www.ncbi.nlm.nih.gov/pubmed/29607317
http://dx.doi.org/10.1155/2018/3248289
work_keys_str_mv AT sahuindrad sitedirectedspinlabelingeprforstudyingmembraneproteins
AT lorigangarya sitedirectedspinlabelingeprforstudyingmembraneproteins

Ejemplares similares