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ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model
BACKGROUND: The LIM-homeobox transcription factor islet-1 (ISL1) has been proposed as a marker for cardiovascular progenitor cells. This study investigated whether forced expression of ISL1 in human mesenchymal stem cells (hMSCs) improves myocardial infarction (MI) treatment outcomes. METHODS: The l...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828309/ https://www.ncbi.nlm.nih.gov/pubmed/29482621 http://dx.doi.org/10.1186/s13287-018-0803-7 |