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Characterization of knockin mice at the Rosa26, Tac1 and Plekhg1 loci generated by homologous recombination in oocytes

Design and engineering of complex knockin mice has revolutionized the in vivo manipulation of genetically defined cells. Recently development of the bacterial clustered regularly interspersed short palindromic repeats (CRISPR) associated protein 9 (Cas9) system for single site cleavage of mammalian...

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Detalles Bibliográficos
Autores principales: Wu, Youmei, Luna, María José, Bonilla, Lauren S., Ryba, Nicholas J. P., Pickel, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828354/
https://www.ncbi.nlm.nih.gov/pubmed/29485996
http://dx.doi.org/10.1371/journal.pone.0193129