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Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study

The ACCESS-model offers integrated care including assertive community treatment to patients with psychotic disorders. ACCESS proved more effective compared to standard care (ACCESS-I study) and was successfully implemented into clinical routine (ACCESS-II study). In this article, we report the 4-yea...

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Autores principales: Schöttle, Daniel, Schimmelmann, Benno G., Ruppelt, Friederike, Bussopulos, Alexandra, Frieling, Marietta, Nika, Evangelia, Nawara, Luise Antonia, Golks, Dietmar, Kerstan, Andrea, Lange, Matthias, Schödlbauer, Michael, Daubmann, Anne, Wegscheider, Karl, Rohenkohl, Anja, Sarikaya, Gizem, Sengutta, Mary, Luedecke, Daniel, Wittmann, Linus, Ohm, Gunda, Meigel-Schleiff, Christina, Gallinat, Jürgen, Wiedemann, Klaus, Bock, Thomas, Karow, Anne, Lambert, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828355/
https://www.ncbi.nlm.nih.gov/pubmed/29485988
http://dx.doi.org/10.1371/journal.pone.0192929
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author Schöttle, Daniel
Schimmelmann, Benno G.
Ruppelt, Friederike
Bussopulos, Alexandra
Frieling, Marietta
Nika, Evangelia
Nawara, Luise Antonia
Golks, Dietmar
Kerstan, Andrea
Lange, Matthias
Schödlbauer, Michael
Daubmann, Anne
Wegscheider, Karl
Rohenkohl, Anja
Sarikaya, Gizem
Sengutta, Mary
Luedecke, Daniel
Wittmann, Linus
Ohm, Gunda
Meigel-Schleiff, Christina
Gallinat, Jürgen
Wiedemann, Klaus
Bock, Thomas
Karow, Anne
Lambert, Martin
author_facet Schöttle, Daniel
Schimmelmann, Benno G.
Ruppelt, Friederike
Bussopulos, Alexandra
Frieling, Marietta
Nika, Evangelia
Nawara, Luise Antonia
Golks, Dietmar
Kerstan, Andrea
Lange, Matthias
Schödlbauer, Michael
Daubmann, Anne
Wegscheider, Karl
Rohenkohl, Anja
Sarikaya, Gizem
Sengutta, Mary
Luedecke, Daniel
Wittmann, Linus
Ohm, Gunda
Meigel-Schleiff, Christina
Gallinat, Jürgen
Wiedemann, Klaus
Bock, Thomas
Karow, Anne
Lambert, Martin
author_sort Schöttle, Daniel
collection PubMed
description The ACCESS-model offers integrated care including assertive community treatment to patients with psychotic disorders. ACCESS proved more effective compared to standard care (ACCESS-I study) and was successfully implemented into clinical routine (ACCESS-II study). In this article, we report the 4-year outcomes of the ACCESS-II study. Between May 2007 and December 2013, 115 patients received continuous ACCESS-care. We hypothesized that the low 2-year disengagement and hospitalization rates and significant improvements in psychopathology, functioning, and quality of life could be sustained over 4 years. Over 4 years, only 10 patients disengaged from ACCESS. Another 23 left for practical reasons and were successfully transferred to other services. Hospitalization rates remained low (13.0% in year 3; 9.1% in year 4). Involuntary admissions decreased from 35% in the 2 years prior to ACCESS to 8% over 4 years in ACCESS. Outpatient contacts remained stably high at 2.0–2.4 per week. We detected significant improvements in psychopathology (effect size d = 0.79), illness severity (d = 1.29), level of functioning (d = 0.77), quality of life (d = 0.47) and stably high client satisfaction (d = 0.02) over 4 years. Most positive effects were observed within the first 2 years with the exception of illness severity, which further improved from year 2 to 4. Within continuous intensive 4-year ACCESS-care, sustained improvements in psychopathology, functioning, quality of life, low service disengagement and re-hospitalization rates, as well as low rates of involuntary treatment, were observed in contrast to other studies, which reported a decline in these parameters once a specific treatment model was stopped. Yet, stronger evidence to prove these results is required. Trial registration: Clinical Trial Registration Number: NCT01888627
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spelling pubmed-58283552018-03-19 Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study Schöttle, Daniel Schimmelmann, Benno G. Ruppelt, Friederike Bussopulos, Alexandra Frieling, Marietta Nika, Evangelia Nawara, Luise Antonia Golks, Dietmar Kerstan, Andrea Lange, Matthias Schödlbauer, Michael Daubmann, Anne Wegscheider, Karl Rohenkohl, Anja Sarikaya, Gizem Sengutta, Mary Luedecke, Daniel Wittmann, Linus Ohm, Gunda Meigel-Schleiff, Christina Gallinat, Jürgen Wiedemann, Klaus Bock, Thomas Karow, Anne Lambert, Martin PLoS One Research Article The ACCESS-model offers integrated care including assertive community treatment to patients with psychotic disorders. ACCESS proved more effective compared to standard care (ACCESS-I study) and was successfully implemented into clinical routine (ACCESS-II study). In this article, we report the 4-year outcomes of the ACCESS-II study. Between May 2007 and December 2013, 115 patients received continuous ACCESS-care. We hypothesized that the low 2-year disengagement and hospitalization rates and significant improvements in psychopathology, functioning, and quality of life could be sustained over 4 years. Over 4 years, only 10 patients disengaged from ACCESS. Another 23 left for practical reasons and were successfully transferred to other services. Hospitalization rates remained low (13.0% in year 3; 9.1% in year 4). Involuntary admissions decreased from 35% in the 2 years prior to ACCESS to 8% over 4 years in ACCESS. Outpatient contacts remained stably high at 2.0–2.4 per week. We detected significant improvements in psychopathology (effect size d = 0.79), illness severity (d = 1.29), level of functioning (d = 0.77), quality of life (d = 0.47) and stably high client satisfaction (d = 0.02) over 4 years. Most positive effects were observed within the first 2 years with the exception of illness severity, which further improved from year 2 to 4. Within continuous intensive 4-year ACCESS-care, sustained improvements in psychopathology, functioning, quality of life, low service disengagement and re-hospitalization rates, as well as low rates of involuntary treatment, were observed in contrast to other studies, which reported a decline in these parameters once a specific treatment model was stopped. Yet, stronger evidence to prove these results is required. Trial registration: Clinical Trial Registration Number: NCT01888627 Public Library of Science 2018-02-27 /pmc/articles/PMC5828355/ /pubmed/29485988 http://dx.doi.org/10.1371/journal.pone.0192929 Text en © 2018 Schöttle et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Schöttle, Daniel
Schimmelmann, Benno G.
Ruppelt, Friederike
Bussopulos, Alexandra
Frieling, Marietta
Nika, Evangelia
Nawara, Luise Antonia
Golks, Dietmar
Kerstan, Andrea
Lange, Matthias
Schödlbauer, Michael
Daubmann, Anne
Wegscheider, Karl
Rohenkohl, Anja
Sarikaya, Gizem
Sengutta, Mary
Luedecke, Daniel
Wittmann, Linus
Ohm, Gunda
Meigel-Schleiff, Christina
Gallinat, Jürgen
Wiedemann, Klaus
Bock, Thomas
Karow, Anne
Lambert, Martin
Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title_full Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title_fullStr Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title_full_unstemmed Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title_short Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study
title_sort effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar i disorders: four-year follow-up of the access ii study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828355/
https://www.ncbi.nlm.nih.gov/pubmed/29485988
http://dx.doi.org/10.1371/journal.pone.0192929
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